BDBM332745 6-fluoro-2-(4-(5-trifluoromethylpyrazin-2-yl)piperazin-1-yl)-1H-benzimidazole-4-carboxamide::US10196381, Compound (35)
SMILES: NC(=O)c1cc(F)cc2[nH]c(nc12)N1CCN(CC1)c1cnc(cn1)C(F)(F)F
InChI Key: InChIKey=VXBQDDCNIVLAPQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM332745 (6-fluoro-2-(4-(5-trifluoromethylpyrazin-2-yl)piper...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI HUILUN LIFE SCIENCE &TECHNOLOGY CO., LTD US Patent | Assay Description 1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P... | US Patent US10196381 (2019) BindingDB Entry DOI: 10.7270/Q2TT4T17 | |||||||||||
More data for this Ligand-Target Pair |