BDBM33301 US10849901, Compound 115::rhodanine, 1-2
SMILES: Cc1cccc(c1)N1C(=S)S\C(=C/c2cc(cc(Br)c2O)[N+]([O-])=O)C1=O
InChI Key: InChIKey=QVRWXCIPARSBJT-AUWJEWJLSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADP-ribosylation factor 6 (Human) | BDBM33301![]() (US10849901, Compound 115 | rhodanine, 1-2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Navigen, Inc.; The University of Utah Research Foundation US Patent | Assay Description The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ... | US Patent US10849901 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sortase family protein (Staphylococcus aureus) | BDBM33301![]() (US10849901, Compound 115 | rhodanine, 1-2) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of California at Los Angeles | Assay Description A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ... | Bioorg Med Chem 17: 7174-85 (2009) Article DOI: 10.1016/j.bmc.2009.08.067 BindingDB Entry DOI: 10.7270/Q26W98F0 | |||||||||||
More data for this Ligand-Target Pair |