BDBM333036 US10196391, Example 36

SMILES: Clc1ccc(nc1)N1CCc2nc(ncc2C1)-c1ccccn1

InChI Key: InChIKey=HQAYHFVKDNLMSA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333036 (US10196391, Example 36) Show SMILES Clc1ccc(nc1)N1CCc2nc(ncc2C1)-c1ccccn1 Show InChI InChI=1S/C17H14ClN5/c18-13-4-5-16(20-10-13)23-8-6-14-12(11-23)9-21-17(22-14)15-3-1-2-7-19-15/h1-5,7,9-10H,6,8,11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
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