BDBM333060 US10196391, Example 60

SMILES: COc1cc(ccc1C#N)N1CCc2nc(ncc2C1)-c1ccccn1

InChI Key: InChIKey=PNQBGMCTBOAEBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333060 (US10196391, Example 60) Show SMILES COc1cc(ccc1C#N)N1CCc2nc(ncc2C1)-c1ccccn1 Show InChI InChI=1S/C20H17N5O/c1-26-19-10-16(6-5-14(19)11-21)25-9-7-17-15(13-25)12-23-20(24-17)18-4-2-3-8-22-18/h2-6,8,10,12H,7,9,13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	371	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
					More data for this Ligand-Target Pair