BDBM333380 2-{[3-(1-Benzofuran-2-yl)imidazo[1, 2-b]pyridazin-6-yl]oxy}-N-ethylethanolamine::US9730929, Example 1
SMILES: CCN(CCO)c1ccc2ncc(-c3cc4ccccc4o3)n2n1
InChI Key: InChIKey=UENYIDFFABAYJD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM333380 (2-{[3-(1-Benzofuran-2-yl)imidazo[1, 2-b]pyridazin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n... | US Patent US9730929 (2017) BindingDB Entry DOI: 10.7270/Q28S4S1H | |||||||||||
More data for this Ligand-Target Pair |