null

SMILES: CCC(=O)N1CC[C@@H](C1)Oc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1

InChI Key: InChIKey=YNOLINLXOHNAOX-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM333924 (9-ethyl-8-(2-methylpyrimidin-5- yl)-6-{[(3S)-1- pr...) Show SMILES CCC(=O)N1CC[C@@H](C1)Oc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1 |r| Show InChI InChI=1S/C19H23N7O2/c1-4-15(27)25-7-6-14(10-25)28-19-16-18(22-11-23-19)26(5-2)17(24-16)13-8-20-12(3)21-9-13/h8-9,11,14H,4-7,10H2,1-3H3/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00237 BindingDB Entry DOI: 10.7270/Q28919NT
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM333924 (9-ethyl-8-(2-methylpyrimidin-5- yl)-6-{[(3S)-1- pr...) Show SMILES CCC(=O)N1CC[C@@H](C1)Oc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1 |r| Show InChI InChI=1S/C19H23N7O2/c1-4-15(27)25-7-6-14(10-25)28-19-16-18(22-11-23-19)26(5-2)17(24-16)13-8-20-12(3)21-9-13/h8-9,11,14H,4-7,10H2,1-3H3/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme US Patent					Assay Description The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...				US Patent US9730940 (2017) BindingDB Entry DOI: 10.7270/Q2BP04WX
					More data for this Ligand-Target Pair