null

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CCC1

InChI Key: InChIKey=IRMSFLMMCDOYQT-HSNGWXBGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM336460 (US9744172, Compound UNC1148A) Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CCC1 |r,wD:15.15,(-7.06,-3.34,;-5.73,-2.57,;-4.4,-3.34,;-3.06,-2.57,;-1.73,-3.34,;-.4,-2.57,;-.4,-1.03,;.94,-.26,;2.27,-1.03,;3.74,-.55,;4.64,-1.8,;3.74,-3.04,;4.14,-4.53,;5.62,-4.93,;6.02,-6.42,;4.93,-7.5,;5.33,-8.99,;3.45,-7.11,;3.05,-5.62,;2.27,-2.57,;.94,-3.34,;4.14,.94,;5.62,1.34,;6.02,2.82,;4.93,3.91,;3.45,3.51,;3.05,2.03,;5.33,5.4,;3.84,5.8,;6.82,5,;5.73,6.89,;7.06,7.66,;6.29,8.99,;4.96,8.22,)| Show InChI InChI=1S/C24H32N6O3S/c1-2-3-13-25-24-26-16-21-22(28-30(23(21)27-24)18-7-9-19(31)10-8-18)17-5-11-20(12-6-17)34(32,33)29-14-4-15-29/h5-6,11-12,16,18-19,31H,2-4,7-10,13-15H2,1H3,(H,25,26,27)/t18?,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...				US Patent US9744172 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z30
					More data for this Ligand-Target Pair