BDBM336540 1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)- 2,2,2- trifluoroethanone::US9745282, 32

SMILES: Fc1cncc(c1)-c1cc2CCN(C(=O)C(F)(F)F)c2c(Cl)c1

InChI Key: InChIKey=GQLSZAQYIVRDJO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM336540 (1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)-...) Show SMILES Fc1cncc(c1)-c1cc2CCN(C(=O)C(F)(F)F)c2c(Cl)c1 Show InChI InChI=1S/C15H9ClF4N2O/c16-12-5-9(10-4-11(17)7-21-6-10)3-8-1-2-22(13(8)12)14(23)15(18,19)20/h3-7H,1-2H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent									US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM336540 (1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)-...) Show SMILES Fc1cncc(c1)-c1cc2CCN(C(=O)C(F)(F)F)c2c(Cl)c1 Show InChI InChI=1S/C15H9ClF4N2O/c16-12-5-9(10-4-11(17)7-21-6-10)3-8-1-2-22(13(8)12)14(23)15(18,19)20/h3-7H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair