null

SMILES: CC(=O)Nc1cc(cn2nccc12)-c1ccnc(Nc2ccnc(n2)C2CC2)c1

InChI Key: InChIKey=YFRHWKGGNQRORI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338190 (US9751854, Compound I-371) Show SMILES CC(=O)Nc1cc(cn2nccc12)-c1ccnc(Nc2ccnc(n2)C2CC2)c1 Show InChI InChI=1S/C21H19N7O/c1-13(29)25-17-10-16(12-28-18(17)5-9-24-28)15-4-7-22-20(11-15)26-19-6-8-23-21(27-19)14-2-3-14/h4-12,14H,2-3H2,1H3,(H,25,29)(H,22,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair