null

SMILES: CN(C)S(=O)(=O)Nc1c(Cl)ncc(c1C)-c1ccnc(Nc2ccnc(C)n2)c1

InChI Key: InChIKey=PIVHURGZHDITTH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338200 (US9751854, Compound I-381 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)Nc1c(Cl)ncc(c1C)-c1ccnc(Nc2ccnc(C)n2)c1 Show InChI InChI=1S/C18H20ClN7O2S/c1-11-14(10-22-18(19)17(11)25-29(27,28)26(3)4)13-5-7-21-16(9-13)24-15-6-8-20-12(2)23-15/h5-10,25H,1-4H3,(H,20,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9802960 (2017) BindingDB Entry DOI: 10.7270/Q2D79DJ9
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338200 (US9751854, Compound I-381 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)Nc1c(Cl)ncc(c1C)-c1ccnc(Nc2ccnc(C)n2)c1 Show InChI InChI=1S/C18H20ClN7O2S/c1-11-14(10-22-18(19)17(11)25-29(27,28)26(3)4)13-5-7-21-16(9-13)24-15-6-8-20-12(2)23-15/h5-10,25H,1-4H3,(H,20,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair