BDBM338970 US10201527, Compound 65

SMILES: CN1\C(=C\c2ccccc2)N(O)c2cc(\C=C\C(=O)NO)ccc12

InChI Key: InChIKey=SDASCCZKEYGRNJ-BLPDYOKRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM338970 (US10201527, Compound 65) Show SMILES CN1\C(=C\c2ccccc2)N(O)c2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C18H17N3O3/c1-20-15-9-7-14(8-10-17(22)19-23)11-16(15)21(24)18(20)12-13-5-3-2-4-6-13/h2-12,23-24H,1H3,(H,19,22)/b10-8+,18-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
MEI PHARMA, INC. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10201527 (2019) BindingDB Entry DOI: 10.7270/Q2PK0J7F
					More data for this Ligand-Target Pair