BDBM33964 maleimide derivative, 3

SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12

InChI Key: InChIKey=OCPILGAGUGFNJE-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein Kinase C, eta (Homo sapiens (Human))	BDBM33964 (maleimide derivative, 3) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C27H25N3O2/c1-29(2)15-8-16-30-17-22(20-12-5-6-14-23(20)30)25-24(26(31)28-27(25)32)21-13-7-10-18-9-3-4-11-19(18)21/h3-7,9-14,17H,8,15-16H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair