BDBM33965 maleimide derivative, 4

SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12

InChI Key: InChIKey=XIYBTJNOANAUDQ-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein Kinase C, eta (Homo sapiens (Human))	BDBM33965 (maleimide derivative, 4) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2n[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-28(2)12-7-13-29-14-17(15-8-4-6-11-19(15)29)20-21(24(31)25-23(20)30)22-16-9-3-5-10-18(16)26-27-22/h3-6,8-11,14H,7,12-13H2,1-2H3,(H,26,27)(H,25,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>315	n/a	n/a	n/a	n/a	n/a	25
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair