null

SMILES: COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12

InChI Key: InChIKey=ALHTUYGSCDRGMC-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 341005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM341005 (US9763952, Example E1 | US9763952, Example F1 | {(...) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12 |r| Show InChI InChI=1S/C23H30N4O5/c1-15-10-16(12-25-21(15)29-5)27-8-9-30-19-13-24-20(11-18(19)27)31-17-6-7-26(14-17)22(28)32-23(2,3)4/h10-13,17H,6-9,14H2,1-5H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...				US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM341005 (US9763952, Example E1 | US9763952, Example F1 | {(...) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12 |r| Show InChI InChI=1S/C23H30N4O5/c1-15-10-16(12-25-21(15)29-5)27-8-9-30-19-13-24-20(11-18(19)27)31-17-6-7-26(14-17)22(28)32-23(2,3)4/h10-13,17H,6-9,14H2,1-5H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM341005 (US9763952, Example E1 | US9763952, Example F1 | {(...) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12 |r| Show InChI InChI=1S/C23H30N4O5/c1-15-10-16(12-25-21(15)29-5)27-8-9-30-19-13-24-20(11-18(19)27)31-17-6-7-26(14-17)22(28)32-23(2,3)4/h10-13,17H,6-9,14H2,1-5H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...				US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM341005 (US9763952, Example E1 | US9763952, Example F1 | {(...) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12 |r| Show InChI InChI=1S/C23H30N4O5/c1-15-10-16(12-25-21(15)29-5)27-8-9-30-19-13-24-20(11-18(19)27)31-17-6-7-26(14-17)22(28)32-23(2,3)4/h10-13,17H,6-9,14H2,1-5H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair