BDBM34191 (2-methoxyphenyl)-(3-methylsulfanyl-6,7-dihydro-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl)methanone::(2-methoxyphenyl)-[3-(methylthio)-6,7-dihydro-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl]methanone::MLS000111412::SMR000107336::cid_2906776
SMILES: COc1ccccc1C(=O)C1Nc2ccccc2-c2nnc(SC)nc2O1
InChI Key: InChIKey=SVRHZTFGWDYKCB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bfl-1 (Mus musculus (Mouse)) | BDBM34191![]() ((2-methoxyphenyl)-(3-methylsulfanyl-6,7-dihydro-[1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | 7.0 | 23 |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description The aim is to identify chemical probes of Bfl-1 through a fluorescence polarization assay (FPA) using FITC-Bid BH3 peptide. 1) Dose-response curves c... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2N014W6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
LANA (Human herpesvirus 8) | BDBM34191![]() ((2-methoxyphenyl)-(3-methylsulfanyl-6,7-dihydro-[1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | >7.50E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2HH6HHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bfl-1 (Mus musculus (Mouse)) | BDBM34191![]() ((2-methoxyphenyl)-(3-methylsulfanyl-6,7-dihydro-[1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2K072NW | |||||||||||
More data for this Ligand-Target Pair |