BDBM343694 (-)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]oxy}-N-methyl-2-phenylethanamine::US9777004, 29

SMILES: CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1

InChI Key: InChIKey=KEWYBDGERGQLDK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343694 ((-)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridaz...) Show SMILES CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 Show InChI InChI=1S/C23H20N4O2/c1-24-15-21(16-7-3-2-4-8-16)29-23-12-11-22-25-14-18(27(22)26-23)20-13-17-9-5-6-10-19(17)28-20/h2-14,21,24H,15H2,1H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343694 ((-)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridaz...) Show SMILES CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 Show InChI InChI=1S/C23H20N4O2/c1-24-15-21(16-7-3-2-4-8-16)29-23-12-11-22-25-14-18(27(22)26-23)20-13-17-9-5-6-10-19(17)28-20/h2-14,21,24H,15H2,1H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair