BDBM344425 US9783500, Compound (R)-19

SMILES: CN[C@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1

InChI Key: InChIKey=PKYCUWKYSZUTFJ-GFCCVEGCSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 344425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM344425 (US9783500, Compound (R)-19) Show SMILES CN[C@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1 |r| Show InChI InChI=1S/C18H20N4O/c1-12(20-2)15-8-16(10-21-9-15)23-11-13-3-4-14-5-6-18(19)22-17(14)7-13/h3-10,12,20H,11H2,1-2H3,(H2,19,22)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University US Patent					Assay Description Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...				US Patent US9783500 (2017) BindingDB Entry DOI: 10.7270/Q2930WBP
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM344425 (US9783500, Compound (R)-19) Show SMILES CN[C@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1 |r| Show InChI InChI=1S/C18H20N4O/c1-12(20-2)15-8-16(10-21-9-15)23-11-13-3-4-14-5-6-18(19)22-17(14)7-13/h3-10,12,20H,11H2,1-2H3,(H2,19,22)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University US Patent					Assay Description Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...				US Patent US9783500 (2017) BindingDB Entry DOI: 10.7270/Q2930WBP
					More data for this Ligand-Target Pair
Nitric-oxide synthase, brain (Mus musculus)	BDBM344425 (US9783500, Compound (R)-19) Show SMILES CN[C@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1 |r| Show InChI InChI=1S/C18H20N4O/c1-12(20-2)15-8-16(10-21-9-15)23-11-13-3-4-14-5-6-18(19)22-17(14)7-13/h3-10,12,20H,11H2,1-2H3,(H2,19,22)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University US Patent					Assay Description Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...				US Patent US9783500 (2017) BindingDB Entry DOI: 10.7270/Q2930WBP
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM344425 (US9783500, Compound (R)-19) Show SMILES CN[C@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1 |r| Show InChI InChI=1S/C18H20N4O/c1-12(20-2)15-8-16(10-21-9-15)23-11-13-3-4-14-5-6-18(19)22-17(14)7-13/h3-10,12,20H,11H2,1-2H3,(H2,19,22)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University US Patent					Assay Description Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...				US Patent US9783500 (2017) BindingDB Entry DOI: 10.7270/Q2930WBP
					More data for this Ligand-Target Pair