BDBM345886 US10202367, Compound 32

SMILES: CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1ccc(C)cc1C

InChI Key: InChIKey=IJDOFGVONPNWFB-GWLNTFQOSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345886 (US10202367, Compound 32) Show SMILES CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1ccc(C)cc1C |r,c:3| Show InChI InChI=1S/C29H46N4O2/c1-20-7-8-26(23(4)16-20)29-31-27(24(5)35-29)19-32-13-9-25(10-14-32)28(34)30-11-6-12-33-17-21(2)15-22(3)18-33/h7-8,16,21-22,24-25,27H,6,9-15,17-19H2,1-5H3,(H,30,34)/t21-,22+,24?,27?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
					More data for this Ligand-Target Pair