BDBM346983 US10202379, Reference Example 724

SMILES: CCc1cccc2CSc3c(F)cccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12

InChI Key: InChIKey=PMEODFRRPNLIRU-SPLOXXLWSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346983 (US10202379, Reference Example 724) Show SMILES CCc1cccc2CSc3c(F)cccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12 |r| Show InChI InChI=1S/C26H23F4N3O3S/c1-3-15-6-4-7-16-12-37-24-17(8-5-9-18(24)27)21(20(15)16)33-13-31(14(2)26(28,29)30)25(36)22-23(35)19(34)10-11-32(22)33/h4-11,14,21,35H,3,12-13H2,1-2H3/t14-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.33	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346983 (US10202379, Reference Example 724) Show SMILES CCc1cccc2CSc3c(F)cccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12 |r| Show InChI InChI=1S/C26H23F4N3O3S/c1-3-15-6-4-7-16-12-37-24-17(8-5-9-18(24)27)21(20(15)16)33-13-31(14(2)26(28,29)30)25(36)22-23(35)19(34)10-11-32(22)33/h4-11,14,21,35H,3,12-13H2,1-2H3/t14-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.07	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair