BDBM347264 US10202411, Compound 326

SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O

InChI Key: InChIKey=NKTQCJIRNHTYAB-HUKYDQBMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NS3 serine protease (NS3) (Hepatitis C Virus (Virus))	BDBM347264 (US10202411, Compound 326) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O |r| Show InChI InChI=1S/C11H17FN5O12P3/c12-1-5-6(2-26-31(22,23)29-32(24,25)28-30(19,20)21)27-11(8(5)18)17-4-16-7-9(13)14-3-15-10(7)17/h3-6,8,11,18H,1-2H2,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/t5-,6-,8-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10202411 (2019) BindingDB Entry DOI: 10.7270/Q2RX9F67
					More data for this Ligand-Target Pair