Found 3 hits for monomerid = 347490 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM347490
(US9790180, ID 023)Show SMILES CCC1(CCN(CC1)C(=O)N1CCNCC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C29H36N6O2S/c1-2-29(11-15-34(16-12-29)28(37)35-17-13-31-14-18-35)33-23-8-5-21(6-9-23)27(36)32-25-20-22(7-10-24(25)30)26-4-3-19-38-26/h3-10,19-20,31,33H,2,11-18,30H2,1H3,(H,32,36) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM347490
(US9790180, ID 023)Show SMILES CCC1(CCN(CC1)C(=O)N1CCNCC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C29H36N6O2S/c1-2-29(11-15-34(16-12-29)28(37)35-17-13-31-14-18-35)33-23-8-5-21(6-9-23)27(36)32-25-20-22(7-10-24(25)30)26-4-3-19-38-26/h3-10,19-20,31,33H,2,11-18,30H2,1H3,(H,32,36) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 267 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM347490
(US9790180, ID 023)Show SMILES CCC1(CCN(CC1)C(=O)N1CCNCC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C29H36N6O2S/c1-2-29(11-15-34(16-12-29)28(37)35-17-13-31-14-18-35)33-23-8-5-21(6-9-23)27(36)32-25-20-22(7-10-24(25)30)26-4-3-19-38-26/h3-10,19-20,31,33H,2,11-18,30H2,1H3,(H,32,36) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |