BDBM348142 US9790228, Compound 61

SMILES: Nc1ncnc2n(Cc3cnc4ccccc4c3)nc(-c3cc(O)cc(F)c3)c12

InChI Key: InChIKey=KDACVAQFKYXPBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348142 (US9790228, Compound 61) Show SMILES Nc1ncnc2n(Cc3cnc4ccccc4c3)nc(-c3cc(O)cc(F)c3)c12 Show InChI InChI=1S/C21H15FN6O/c22-15-6-14(7-16(29)8-15)19-18-20(23)25-11-26-21(18)28(27-19)10-12-5-13-3-1-2-4-17(13)24-9-12/h1-9,11,29H,10H2,(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348142 (US9790228, Compound 61) Show SMILES Nc1ncnc2n(Cc3cnc4ccccc4c3)nc(-c3cc(O)cc(F)c3)c12 Show InChI InChI=1S/C21H15FN6O/c22-15-6-14(7-16(29)8-15)19-18-20(23)25-11-26-21(18)28(27-19)10-12-5-13-3-1-2-4-17(13)24-9-12/h1-9,11,29H,10H2,(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair