BDBM348689 N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]-5-(2,2,2-trifluoroethoxy)pyridine-2-carboxamide::US9790230, Example 51

SMILES: FC(F)(F)COc1ccc(nc1)C(=O)Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2

InChI Key: InChIKey=RHHFCEZIYQMAKN-BHYGNILZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM348689 (N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...) Show SMILES FC(F)(F)COc1ccc(nc1)C(=O)Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2 |r| Show InChI InChI=1S/C19H18F3N3O3/c20-19(21,22)10-27-13-5-6-15(23-8-13)18(26)25-12-3-1-11(2-4-12)17-16-7-14(28-17)9-24-16/h1-6,8,14,16-17,24H,7,9-10H2,(H,25,26)/t14-,16-,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.8	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9790230 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T8R
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM348689 (N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...) Show SMILES FC(F)(F)COc1ccc(nc1)C(=O)Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2 |r| Show InChI InChI=1S/C19H18F3N3O3/c20-19(21,22)10-27-13-5-6-15(23-8-13)18(26)25-12-3-1-11(2-4-12)17-16-7-14(28-17)9-24-16/h1-6,8,14,16-17,24H,7,9-10H2,(H,25,26)/t14-,16-,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9790230 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T8R
					More data for this Ligand-Target Pair