BDBM348700 N-(6-Ethoxy-3-pyridyl)-4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]benzamide::US9790230, Example 62

SMILES: CCOc1ccc(NC(=O)c2ccc(cc2)[C@H]2O[C@@H]3CN[C@H]2C3)cn1

InChI Key: InChIKey=XWOMTMCRCYGJBH-XYJFISCASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM348700 (N-(6-Ethoxy-3-pyridyl)-4-[(1S,3R,4S)-2-oxa-5-azabi...) Show SMILES CCOc1ccc(NC(=O)c2ccc(cc2)[C@H]2O[C@@H]3CN[C@H]2C3)cn1 |r| Show InChI InChI=1S/C19H21N3O3/c1-2-24-17-8-7-14(10-21-17)22-19(23)13-5-3-12(4-6-13)18-16-9-15(25-18)11-20-16/h3-8,10,15-16,18,20H,2,9,11H2,1H3,(H,22,23)/t15-,16-,18+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9790230 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T8R
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM348700 (N-(6-Ethoxy-3-pyridyl)-4-[(1S,3R,4S)-2-oxa-5-azabi...) Show SMILES CCOc1ccc(NC(=O)c2ccc(cc2)[C@H]2O[C@@H]3CN[C@H]2C3)cn1 |r| Show InChI InChI=1S/C19H21N3O3/c1-2-24-17-8-7-14(10-21-17)22-19(23)13-5-3-12(4-6-13)18-16-9-15(25-18)11-20-16/h3-8,10,15-16,18,20H,2,9,11H2,1H3,(H,22,23)/t15-,16-,18+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9790230 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T8R
					More data for this Ligand-Target Pair