BDBM34916 6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,5,6-tetrahydro[1,3]thiazolo[4,5-d]pyrimidin-7(4H)-one::6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-4H-thiazolo[4,5-d]pyrimidin-7-one;triethylamine::MLS000621888::N,N-diethylethanamine;6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-bis(sulfanylidene)-4H-[1,3]thiazolo[4,5-d]pyrimidin-7-one::N,N-diethylethanamine;6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-bis(sulfanylidene)-4H-thiazolo[4,5-d]pyrimidin-7-one::SMR000310815::cid_16193566

SMILES: COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O

InChI Key: InChIKey=JASTXBOVJBDOQP-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 34916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MPI protein (Homo sapiens (Human))	BDBM34916 (6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,...) Show SMILES COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O |(.95,.95,;.95,2.49,;2.29,3.26,;3.62,2.49,;4.96,3.26,;4.96,4.8,;3.62,5.57,;3.62,7.11,;2.29,7.88,;2.29,4.8,;6.29,5.57,;6.29,7.11,;4.96,7.88,;7.62,7.88,;8.96,7.11,;10.41,7.58,;10.89,9.05,;12.4,9.37,;12.88,10.83,;11.85,11.98,;10.34,11.66,;9.86,10.19,;11.31,6.34,;12.85,6.34,;10.41,5.11,;8.96,5.57,;7.62,4.8,;7.62,3.26,)| Show InChI InChI=1S/C19H15N3O3S3/c1-24-12-8-9-13(14(10-12)25-2)22-17(23)15-16(20-18(22)26)21(19(27)28-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,20,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.76E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2CF9NFM
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34916 (6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,...) Show SMILES COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O |(.95,.95,;.95,2.49,;2.29,3.26,;3.62,2.49,;4.96,3.26,;4.96,4.8,;3.62,5.57,;3.62,7.11,;2.29,7.88,;2.29,4.8,;6.29,5.57,;6.29,7.11,;4.96,7.88,;7.62,7.88,;8.96,7.11,;10.41,7.58,;10.89,9.05,;12.4,9.37,;12.88,10.83,;11.85,11.98,;10.34,11.66,;9.86,10.19,;11.31,6.34,;12.85,6.34,;10.41,5.11,;8.96,5.57,;7.62,4.8,;7.62,3.26,)| Show InChI InChI=1S/C19H15N3O3S3/c1-24-12-8-9-13(14(10-12)25-2)22-17(23)15-16(20-18(22)26)21(19(27)28-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,20,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2ZS2TZG
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34916 (6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,...) Show SMILES COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O |(.95,.95,;.95,2.49,;2.29,3.26,;3.62,2.49,;4.96,3.26,;4.96,4.8,;3.62,5.57,;3.62,7.11,;2.29,7.88,;2.29,4.8,;6.29,5.57,;6.29,7.11,;4.96,7.88,;7.62,7.88,;8.96,7.11,;10.41,7.58,;10.89,9.05,;12.4,9.37,;12.88,10.83,;11.85,11.98,;10.34,11.66,;9.86,10.19,;11.31,6.34,;12.85,6.34,;10.41,5.11,;8.96,5.57,;7.62,4.8,;7.62,3.26,)| Show InChI InChI=1S/C19H15N3O3S3/c1-24-12-8-9-13(14(10-12)25-2)22-17(23)15-16(20-18(22)26)21(19(27)28-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,20,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23T9FQ1
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34916 (6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,...) Show SMILES COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O |(.95,.95,;.95,2.49,;2.29,3.26,;3.62,2.49,;4.96,3.26,;4.96,4.8,;3.62,5.57,;3.62,7.11,;2.29,7.88,;2.29,4.8,;6.29,5.57,;6.29,7.11,;4.96,7.88,;7.62,7.88,;8.96,7.11,;10.41,7.58,;10.89,9.05,;12.4,9.37,;12.88,10.83,;11.85,11.98,;10.34,11.66,;9.86,10.19,;11.31,6.34,;12.85,6.34,;10.41,5.11,;8.96,5.57,;7.62,4.8,;7.62,3.26,)| Show InChI InChI=1S/C19H15N3O3S3/c1-24-12-8-9-13(14(10-12)25-2)22-17(23)15-16(20-18(22)26)21(19(27)28-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,20,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q27H1H3W
					More data for this Ligand-Target Pair
Glucose 6-phosphate dehydrogenase (G6PD) (Homo sapiens (Human))	BDBM34916 (6-(2,4-dimethoxyphenyl)-3-phenyl-2,5-dithioxo-2,3,...) Show SMILES COc1ccc(c(OC)c1)-n1c(=S)[nH]c2n(-c3ccccc3)c(=S)sc2c1=O |(.95,.95,;.95,2.49,;2.29,3.26,;3.62,2.49,;4.96,3.26,;4.96,4.8,;3.62,5.57,;3.62,7.11,;2.29,7.88,;2.29,4.8,;6.29,5.57,;6.29,7.11,;4.96,7.88,;7.62,7.88,;8.96,7.11,;10.41,7.58,;10.89,9.05,;12.4,9.37,;12.88,10.83,;11.85,11.98,;10.34,11.66,;9.86,10.19,;11.31,6.34,;12.85,6.34,;10.41,5.11,;8.96,5.57,;7.62,4.8,;7.62,3.26,)| Show InChI InChI=1S/C19H15N3O3S3/c1-24-12-8-9-13(14(10-12)25-2)22-17(23)15-16(20-18(22)26)21(19(27)28-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,20,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V12389
					More data for this Ligand-Target Pair