BDBM350104 N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amine::US10208043, # 5::US10941146, # 5
SMILES: CNC1=NC(c2ccccc2)=[N](S1)c1ccccc1
InChI Key: InChIKey=RAAMJXKWHWLWHZ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fascin (Homo sapiens (human)) | BDBM350104![]() (N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVITA PHARMACEUTICALS, INC.; CORNELL UNIVERSITY US Patent | Assay Description A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in... | US Patent US10941146 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fascin (Homo sapiens (human)) | BDBM350104![]() (N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University; Novita Pharmaceuticals, Inc. US Patent | Assay Description About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co... | US Patent US10208043 (2019) BindingDB Entry DOI: 10.7270/Q2VH5QZP | |||||||||||
More data for this Ligand-Target Pair |