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BDBM350521 1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoimidazolidin-1- yl)urea::US10208071, Table 2.2::US10434112, Table 2.2::US10799518, Structure TABLE 2.2

SMILES: CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=ZGKLRHHWQLBTCW-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350521
PNG
(1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoi...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C13H15ClN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
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PC sid
UniChem
US Patent
n/an/an/an/a 1.57E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)


BindingDB Entry DOI: 10.7270/Q2TH8PT9
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350521
PNG
(1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoi...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C13H15ClN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 157n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10799518 (2020)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350521
PNG
(1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoi...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C13H15ClN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 157n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)


BindingDB Entry DOI: 10.7270/Q2HX1G16
More data for this
Ligand-Target Pair