null

SMILES: CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O

InChI Key: InChIKey=DRLYWWBSFZDWQA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350523 (1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-...) Show SMILES CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O |(-6.85,-3.59,;-5.76,-2.5,;-6.16,-1.01,;-5.07,.08,;-3.58,-.32,;-3.19,-1.81,;-4.27,-2.9,;-4.06,1.14,;-2.81,2.05,;-2.81,3.59,;-1.57,1.14,;-.08,1.54,;1.01,.45,;.61,-1.03,;2.5,.85,;3.58,-.24,;3.19,-1.73,;4.27,-2.81,;5.76,-2.42,;6.85,-3.5,;6.16,-.93,;5.07,.16,;-2.04,-.32,;-1.27,-1.66,)| Show InChI InChI=1S/C17H22N4O3/c1-11-3-5-13(6-4-11)18-15(23)20-21-14(22)17(19-16(21)24)9-7-12(2)8-10-17/h3-6,12H,7-10H2,1-2H3,(H,19,24)(H2,18,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.63E+5	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10208071 (2019) BindingDB Entry DOI: 10.7270/Q2TH8PT9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350523 (1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-...) Show SMILES CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O |(-6.85,-3.59,;-5.76,-2.5,;-6.16,-1.01,;-5.07,.08,;-3.58,-.32,;-3.19,-1.81,;-4.27,-2.9,;-4.06,1.14,;-2.81,2.05,;-2.81,3.59,;-1.57,1.14,;-.08,1.54,;1.01,.45,;.61,-1.03,;2.5,.85,;3.58,-.24,;3.19,-1.73,;4.27,-2.81,;5.76,-2.42,;6.85,-3.5,;6.16,-.93,;5.07,.16,;-2.04,-.32,;-1.27,-1.66,)| Show InChI InChI=1S/C17H22N4O3/c1-11-3-5-13(6-4-11)18-15(23)20-21-14(22)17(19-16(21)24)9-7-12(2)8-10-17/h3-6,12H,7-10H2,1-2H3,(H,19,24)(H2,18,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10799518 (2020) BindingDB Entry DOI: 10.7270/Q2QV3QK6
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350523 (1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-...) Show SMILES CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O |(-6.85,-3.59,;-5.76,-2.5,;-6.16,-1.01,;-5.07,.08,;-3.58,-.32,;-3.19,-1.81,;-4.27,-2.9,;-4.06,1.14,;-2.81,2.05,;-2.81,3.59,;-1.57,1.14,;-.08,1.54,;1.01,.45,;.61,-1.03,;2.5,.85,;3.58,-.24,;3.19,-1.73,;4.27,-2.81,;5.76,-2.42,;6.85,-3.5,;6.16,-.93,;5.07,.16,;-2.04,-.32,;-1.27,-1.66,)| Show InChI InChI=1S/C17H22N4O3/c1-11-3-5-13(6-4-11)18-15(23)20-21-14(22)17(19-16(21)24)9-7-12(2)8-10-17/h3-6,12H,7-10H2,1-2H3,(H,19,24)(H2,18,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10434112 (2019) BindingDB Entry DOI: 10.7270/Q2HX1G16
					More data for this Ligand-Target Pair