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BDBM350526 N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazolidin-1-yl)acetamide::US10208071, Table 3.2::US10434112, Table 3.2::US10799518, Structure TABLE 3.2

SMILES: CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O

InChI Key: InChIKey=SIZAXIVFKSSJKA-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350526   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350526
PNG
(N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C15H18BrN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 9.60E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)


BindingDB Entry DOI: 10.7270/Q2TH8PT9
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350526
PNG
(N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C15H18BrN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
PDB

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Reactome pathway
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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 96n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10799518 (2020)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350526
PNG
(N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C15H18BrN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 96n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)


BindingDB Entry DOI: 10.7270/Q2HX1G16
More data for this
Ligand-Target Pair