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SMILES: CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(C)=O

InChI Key: InChIKey=BUSUMBOLRYXBJC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM351018 (6-[4-[(1-Acetyl-4-piperidyl)methyl]-1H-pyrazol-3-y...) Show SMILES CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(C)=O Show InChI InChI=1S/C21H26N4O2/c1-14(26)25-9-7-15(8-10-25)11-18-13-22-23-21(18)17-3-5-19-16(12-17)4-6-20(27)24(19)2/h3,5,12-13,15H,4,6-11H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.266	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM351018 (6-[4-[(1-Acetyl-4-piperidyl)methyl]-1H-pyrazol-3-y...) Show SMILES CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(C)=O Show InChI InChI=1S/C21H26N4O2/c1-14(26)25-9-7-15(8-10-25)11-18-13-22-23-21(18)17-3-5-19-16(12-17)4-6-20(27)24(19)2/h3,5,12-13,15H,4,6-11H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0280	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair