BDBM351201 1-Methyl-6-[4-[[1-(1-methylpyrazole-4-carbonyl)-4-piperidyl]methyl]-1H-pyrazol-3-yl]-3,4-dihydroquinolin-2-one::US9796702, 17

SMILES: CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1cnn(C)c1

InChI Key: InChIKey=KBEMHUWBBMUGIC-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM351201 (1-Methyl-6-[4-[[1-(1-methylpyrazole-4-carbonyl)-4-...) Show SMILES CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1cnn(C)c1 Show InChI InChI=1S/C24H28N6O2/c1-28-15-20(14-26-28)24(32)30-9-7-16(8-10-30)11-19-13-25-27-23(19)18-3-5-21-17(12-18)4-6-22(31)29(21)2/h3,5,12-16H,4,6-11H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM351201 (1-Methyl-6-[4-[[1-(1-methylpyrazole-4-carbonyl)-4-...) Show SMILES CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1cnn(C)c1 Show InChI InChI=1S/C24H28N6O2/c1-28-15-20(14-26-28)24(32)30-9-7-16(8-10-30)11-19-13-25-27-23(19)18-3-5-21-17(12-18)4-6-22(31)29(21)2/h3,5,12-16H,4,6-11H2,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00700	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair