BDBM35123 5-vinyl-3-pyridinecarbonitrile, 12b

SMILES: CN1CCN(CC\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key: InChIKey=COOZRRUJSWPFHC-HWKANZROSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM35123 (5-vinyl-3-pyridinecarbonitrile, 12b) Show SMILES CN1CCN(CC\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C24H28N6/c1-18-21-8-9-27-23(21)7-6-22(18)28-24-19(16-26-17-20(24)15-25)5-3-4-10-30-13-11-29(2)12-14-30/h3,5-9,16-17,27H,4,10-14H2,1-2H3,(H,26,28)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM35123 (5-vinyl-3-pyridinecarbonitrile, 12b) Show SMILES CN1CCN(CC\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C24H28N6/c1-18-21-8-9-27-23(21)7-6-22(18)28-24-19(16-26-17-20(24)15-25)5-3-4-10-30-13-11-29(2)12-14-30/h3,5-9,16-17,27H,4,10-14H2,1-2H3,(H,26,28)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.2	22
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair