BDBM351258 6-[4-[(1-Acetylpiperidin-4-yl)methyl]-1H-pyrazol-3-yl]-7-fluoro-1-methyl-3,4-dihydroquinolin-2-one::US9796702, 19

SMILES: CN1C(=O)CCc2cc(-c3n[nH]cc3CC3CCN(CC3)C(C)=O)c(F)cc12

InChI Key: InChIKey=QXVSFWNQXROXNL-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM351258 (6-[4-[(1-Acetylpiperidin-4-yl)methyl]-1H-pyrazol-3...) Show SMILES CN1C(=O)CCc2cc(-c3n[nH]cc3CC3CCN(CC3)C(C)=O)c(F)cc12 Show InChI InChI=1S/C21H25FN4O2/c1-13(27)26-7-5-14(6-8-26)9-16-12-23-24-21(16)17-10-15-3-4-20(28)25(2)19(15)11-18(17)22/h10-12,14H,3-9H2,1-2H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.416	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM351258 (6-[4-[(1-Acetylpiperidin-4-yl)methyl]-1H-pyrazol-3...) Show SMILES CN1C(=O)CCc2cc(-c3n[nH]cc3CC3CCN(CC3)C(C)=O)c(F)cc12 Show InChI InChI=1S/C21H25FN4O2/c1-13(27)26-7-5-14(6-8-26)9-16-12-23-24-21(16)17-10-15-3-4-20(28)25(2)19(15)11-18(17)22/h10-12,14H,3-9H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair