BDBM35126 5-vinyl-3-pyridinecarbonitrile, 13b

SMILES: Cc1c(Nc2c(\C=C\CCN3CCNCC3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=BUCGAQTZOOCIRW-DUXPYHPUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM35126 (5-vinyl-3-pyridinecarbonitrile, 13b) Show SMILES Cc1c(Nc2c(\C=C\CCN3CCNCC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H26N6/c1-17-20-7-8-27-22(20)6-5-21(17)28-23-18(15-26-16-19(23)14-24)4-2-3-11-29-12-9-25-10-13-29/h2,4-8,15-16,25,27H,3,9-13H2,1H3,(H,26,28)/b4-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM35126 (5-vinyl-3-pyridinecarbonitrile, 13b) Show SMILES Cc1c(Nc2c(\C=C\CCN3CCNCC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H26N6/c1-17-20-7-8-27-22(20)6-5-21(17)28-23-18(15-26-16-19(23)14-24)4-2-3-11-29-12-9-25-10-13-29/h2,4-8,15-16,25,27H,3,9-13H2,1H3,(H,26,28)/b4-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	22
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair