BDBM351267 CHEM-US-00078::US9796702, 28

SMILES: CN1C(=O)CCc2c(Cl)c(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1ncccc1Cl

InChI Key: InChIKey=QFHMCBVOUCXKIU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM351267 (CHEM-US-00078 | US9796702, 28) Show SMILES CN1C(=O)CCc2c(Cl)c(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1ncccc1Cl Show InChI InChI=1S/C25H25Cl2N5O2/c1-31-20-6-4-18(22(27)17(20)5-7-21(31)33)23-16(14-29-30-23)13-15-8-11-32(12-9-15)25(34)24-19(26)3-2-10-28-24/h2-4,6,10,14-15H,5,7-9,11-13H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.45	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM351267 (CHEM-US-00078 | US9796702, 28) Show SMILES CN1C(=O)CCc2c(Cl)c(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1ncccc1Cl Show InChI InChI=1S/C25H25Cl2N5O2/c1-31-20-6-4-18(22(27)17(20)5-7-21(31)33)23-16(14-29-30-23)13-15-8-11-32(12-9-15)25(34)24-19(26)3-2-10-28-24/h2-4,6,10,14-15H,5,7-9,11-13H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0280	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair