BDBM35133 5-vinyl-3-pyridinecarbonitrile, 15c

SMILES: Cc1c(Nc2c(\C=C\CCCN3CCC(O)CC3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=LCLDOTQNYVMPRQ-HWKANZROSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM35133 (5-vinyl-3-pyridinecarbonitrile, 15c) Show SMILES Cc1c(Nc2c(\C=C\CCCN3CCC(O)CC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C25H29N5O/c1-18-22-8-11-28-24(22)7-6-23(18)29-25-19(16-27-17-20(25)15-26)5-3-2-4-12-30-13-9-21(31)10-14-30/h3,5-8,11,16-17,21,28,31H,2,4,9-10,12-14H2,1H3,(H,27,29)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM35133 (5-vinyl-3-pyridinecarbonitrile, 15c) Show SMILES Cc1c(Nc2c(\C=C\CCCN3CCC(O)CC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C25H29N5O/c1-18-22-8-11-28-24(22)7-6-23(18)29-25-19(16-27-17-20(25)15-26)5-3-2-4-12-30-13-9-21(31)10-14-30/h3,5-8,11,16-17,21,28,31H,2,4,9-10,12-14H2,1H3,(H,27,29)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	7.2	22
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair