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SMILES: COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1

InChI Key: InChIKey=LFVVFUDFYJQWPX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM351421 (N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piper...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1 Show InChI InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM351421 (N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piper...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1 Show InChI InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM351421 (N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piper...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1 Show InChI InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM351421 (N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piper...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1 Show InChI InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair