null

SMILES: Cc1c(Nc2c(\C=C\CCN3CCC(CC3)c3ccccc3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=MOJGUBLPDOMBJL-WEVVVXLNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM35149 (5-vinyl-3-pyridinecarbonitrile, 31) Show SMILES Cc1c(Nc2c(\C=C\CCN3CCC(CC3)c3ccccc3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C30H31N5/c1-22-27-12-15-33-29(27)11-10-28(22)34-30-25(20-32-21-26(30)19-31)9-5-6-16-35-17-13-24(14-18-35)23-7-3-2-4-8-23/h2-5,7-12,15,20-21,24,33H,6,13-14,16-18H2,1H3,(H,32,34)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM35149 (5-vinyl-3-pyridinecarbonitrile, 31) Show SMILES Cc1c(Nc2c(\C=C\CCN3CCC(CC3)c3ccccc3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C30H31N5/c1-22-27-12-15-33-29(27)11-10-28(22)34-30-25(20-32-21-26(30)19-31)9-5-6-16-35-17-13-24(14-18-35)23-7-3-2-4-8-23/h2-5,7-12,15,20-21,24,33H,6,13-14,16-18H2,1H3,(H,32,34)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
					More data for this Ligand-Target Pair