BDBM352423 N-((1S*,4S*,7R*)-2-(3-Aminoisoxazolo[5,4-c]pyridin-7-yl)-2-azabicyclo[2.2.1]heptan-7-yl)-2-chloro-4-(3-methyl-1H-1,2,4-triazol-1-yl)benzamide::US9808445, 2

SMILES: Cc1ncn(n1)-c1ccc(C(=O)NC2C3CCC2N(C3)c2nccc3c(N)noc23)c(Cl)c1

InChI Key: InChIKey=WBDHYAPOACOYPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM352423 (N-((1S*,4S*,7R*)-2-(3-Aminoisoxazolo[5,4-c]pyridin...) Show SMILES Cc1ncn(n1)-c1ccc(C(=O)NC2C3CCC2N(C3)c2nccc3c(N)noc23)c(Cl)c1 Show InChI InChI=1S/C22H21ClN8O2/c1-11-26-10-31(28-11)13-3-4-14(16(23)8-13)22(32)27-18-12-2-5-17(18)30(9-12)21-19-15(6-7-25-21)20(24)29-33-19/h3-4,6-8,10,12,17-18H,2,5,9H2,1H3,(H2,24,29)(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp.; Mochida Pharmaceutical Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US9808445 (2017) BindingDB Entry DOI: 10.7270/Q28G8NV1
					More data for this Ligand-Target Pair