BDBM35339 indole-2-carboxamide derivative, 5b

SMILES: OC1CCCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12

InChI Key: InChIKey=MWAVJQBYHXNOOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM35339 (indole-2-carboxamide derivative, 5b) Show SMILES OC1CCCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12 Show InChI InChI=1S/C19H17ClN2O2/c20-13-4-7-16-12(8-13)10-17(22-16)19(24)21-14-5-6-15-11(9-14)2-1-3-18(15)23/h4-10,18,22-23H,1-3H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair