BDBM35689 5H-1-benzazepin-5-ylidene acetamide, 1q
SMILES: Cc1ccn(n1)-c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(O)=O)c3ccccc23)c(Cl)c1
InChI Key: InChIKey=WWYOUXCBBIIJAP-AQTBWJFISA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35689 (5H-1-benzazepin-5-ylidene acetamide, 1q) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 25 | -10.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35689 (5H-1-benzazepin-5-ylidene acetamide, 1q) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.30E+3 | -7.09 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair |