BDBM356926 (R)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)-5- methylpyrrolidin-2- one::US10214507, Compound 113::US10759777, Compound 113

SMILES: C[C@@H]1CCC(=O)N1C[C@@H](O)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=XSVYVGURCRBCTD-HUUCEWRRSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356926 ((R)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)...) Show SMILES C[C@@H]1CCC(=O)N1C[C@@H](O)Cn1c2ccccc2c2ccccc12 |r| Show InChI InChI=1S/C20H22N2O2/c1-14-10-11-20(24)21(14)12-15(23)13-22-18-8-4-2-6-16(18)17-7-3-5-9-19(17)22/h2-9,14-15,23H,10-13H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	948	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020)
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356926 ((R)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)...) Show SMILES C[C@@H]1CCC(=O)N1C[C@@H](O)Cn1c2ccccc2c2ccccc12 |r| Show InChI InChI=1S/C20H22N2O2/c1-14-10-11-20(24)21(14)12-15(23)13-22-18-8-4-2-6-16(18)17-7-3-5-9-19(17)22/h2-9,14-15,23H,10-13H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	948	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair