BDBM3597 (4Z)-4-[(3-bromophenyl)imino]-N,3-dimethyl-3H,4H-pyrido[4,3-d]pyrimidin-7-amine::N4-(3-bromophenyl)-3-methyl-7-(methylamino)-pyrido[4,3-d]pyrimidin-4(3H)-imine::Pyrido[4,3-d]pyrimidine 12

SMILES: CNc1cc2ncn(C)\c(=N/c3cccc(Br)c3)c2cn1

InChI Key: InChIKey=KGPJHDOZKFVFLW-HKWRFOASSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3597 ((4Z)-4-[(3-bromophenyl)imino]-N,3-dimethyl-3H,4H-p...) Show SMILES CNc1cc2ncn(C)\c(=N/c3cccc(Br)c3)c2cn1 Show InChI InChI=1S/C15H14BrN5/c1-17-14-7-13-12(8-18-14)15(21(2)9-19-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,17,18)/b20-15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 39: 1823-35 (1996) Article DOI: 10.1021/jm9508651 BindingDB Entry DOI: 10.7270/Q2X928GF
					More data for this Ligand-Target Pair