null

SMILES: NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O

InChI Key: InChIKey=KAGPCWFBBKVWMA-MDZDMXLPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.273	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0320	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Beta-lactamase ()	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.168	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent									US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.273	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0320	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent									US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM361269 ((S)-4-(2-Amino-1H-benzo[d]imidazol-4-yl)-N1-(1-ami...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N10O5S2/c18-6-8(7-28)25-34(31,32)12-5-4-9(10-2-1-3-11-14(10)22-17(19)21-11)13(15(12)33(20,29)30)16-23-26-27-24-16/h1-5,8,25,28H,6-7,18H2,(H2,19,21)(H2,20,29,30)/b10-9+	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.168	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair