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SMILES: CCn1ncc(c1C)-c1nc2c(NC(C)C(=O)N3CCOCC3)ncnc2n1C

InChI Key: InChIKey=FCVYQXINZPUIGX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))		BDBM361905
PNG
((R or S)-8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-m...)
Show SMILES CCn1ncc(c1C)-c1nc2c(NC(C)C(=O)N3CCOCC3)ncnc2n1C
Show InChI InChI=1S/C19H26N8O2/c1-5-27-13(3)14(10-22-27)17-24-15-16(20-11-21-18(15)25(17)4)23-12(2)19(28)26-6-8-29-9-7-26/h10-12H,5-9H2,1-4H3,(H,20,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 24n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...

US Patent US10221178 (2019)


BindingDB Entry DOI: 10.7270/Q20C4Z2D
More data for this
Ligand-Target Pair