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SMILES: OC[C@@H](NCc1ccc(OCc2cccc(c2Cl)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N)C(O)=O

InChI Key: InChIKey=LAJFPYWWLUHYEA-MUUNZHRXSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363223   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))		BDBM363223
PNG
((R)-2-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]diox...)
Show SMILES OC[C@@H](NCc1ccc(OCc2cccc(c2Cl)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N)C(O)=O |r|
Show InChI InChI=1S/C33H29ClN2O7/c34-32-25(5-2-6-27(32)23-8-10-29-31(14-23)41-12-11-40-29)20-42-26-9-7-24(17-36-28(18-37)33(38)39)30(15-26)43-19-22-4-1-3-21(13-22)16-35/h1-10,13-15,28,36-37H,11-12,17-20H2,(H,38,39)/t28-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.30n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...

US Patent US9850225 (2017)


BindingDB Entry DOI: 10.7270/Q2N018TZ
More data for this
Ligand-Target Pair