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SMILES: Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CNCCO)cc2Cl)cccc1-c1ccc2OCCOc2c1

InChI Key: InChIKey=XFJYWIDIGLRVOI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363249   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))		BDBM363249
PNG
(3-((4-chloro-5-((3-(2,3-dihydrobenzo[b][1,4]dioxin...)
Show SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CNCCO)cc2Cl)cccc1-c1ccc2OCCOc2c1
Show InChI InChI=1S/C33H31ClN2O5/c1-22-26(6-3-7-28(22)25-8-9-30-33(16-25)39-13-12-38-30)21-41-32-17-31(27(15-29(32)34)19-36-10-11-37)40-20-24-5-2-4-23(14-24)18-35/h2-9,14-17,36-37H,10-13,19-21H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 5.30n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...

US Patent US9850225 (2017)


BindingDB Entry DOI: 10.7270/Q2N018TZ
More data for this
Ligand-Target Pair