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SMILES: Cc1noc(C)c1-c1ccc2cnn3C(COc1c23)c1ccccn1

InChI Key: InChIKey=SSSDWWMOVHHNDT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [342-460] (Homo sapiens (Human))	BDBM363501 (US9850257, Example 8) Show SMILES Cc1noc(C)c1-c1ccc2cnn3C(COc1c23)c1ccccn1 |(.13,-2.42,;1.47,-3.19,;1.94,-4.65,;3.48,-4.65,;3.96,-3.19,;5.29,-2.42,;2.71,-2.28,;2.71,-.74,;4.04,.03,;4.04,1.57,;2.71,2.34,;2.71,3.88,;.04,3.88,;.04,2.34,;-1.29,1.57,;-1.29,.03,;.04,-.74,;1.38,.03,;1.38,1.57,;-2.62,2.34,;-2.62,3.88,;-3.96,4.65,;-5.29,3.88,;-5.29,2.34,;-3.96,1.57,)| Show InChI InChI=1S/C19H16N4O2/c1-11-17(12(2)25-22-11)14-7-6-13-9-21-23-16(10-24-19(14)18(13)23)15-5-3-4-8-20-15/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				US Patent US9850257 (2017) BindingDB Entry DOI: 10.7270/Q2CF9SDT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM363501 (US9850257, Example 8) Show SMILES Cc1noc(C)c1-c1ccc2cnn3C(COc1c23)c1ccccn1 |(.13,-2.42,;1.47,-3.19,;1.94,-4.65,;3.48,-4.65,;3.96,-3.19,;5.29,-2.42,;2.71,-2.28,;2.71,-.74,;4.04,.03,;4.04,1.57,;2.71,2.34,;2.71,3.88,;.04,3.88,;.04,2.34,;-1.29,1.57,;-1.29,.03,;.04,-.74,;1.38,.03,;1.38,1.57,;-2.62,2.34,;-2.62,3.88,;-3.96,4.65,;-5.29,3.88,;-5.29,2.34,;-3.96,1.57,)| Show InChI InChI=1S/C19H16N4O2/c1-11-17(12(2)25-22-11)14-7-6-13-9-21-23-16(10-24-19(14)18(13)23)15-5-3-4-8-20-15/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				US Patent US9850257 (2017) BindingDB Entry DOI: 10.7270/Q2CF9SDT
					More data for this Ligand-Target Pair