null
SMILES: CCOc1cc(OC)cc2oc(cc12)-c1cn2nc(OC)sc2n1
InChI Key: InChIKey=WACOTWHRFLODGY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 4 (Homo sapiens (Human)) | BDBM364747![]() (6-(4-Ethoxy, 6-methoxybenzofuran-2-yl)-2-(methylth...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.01 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu... | J Med Chem 48: 6661-70 (2005) BindingDB Entry DOI: 10.7270/Q2X92DKF | |||||||||||
More data for this Ligand-Target Pair |