null
SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3ccc(OC)c(OCc4ccccc4)c3)cc(OC)cc2o1
InChI Key: InChIKey=UCXXUPIMNLLOEK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 4 (Homo sapiens (Human)) | BDBM364893 (US9862730, Example 351) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.23 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu... | J Med Chem 48: 6661-70 (2005) BindingDB Entry DOI: 10.7270/Q2X92DKF | |||||||||||
More data for this Ligand-Target Pair |